Research
Metabolic adaptation
Higher low carbohydrate diet (LCD) score is associated with an increased risk of type 2 diabetes (T2D), with a 20% increased risk observed when comparing the highest quintile (38% energy from carbohydrates) to the lowest quintile (55% energy from carbohydrates).
Practitioners should be cautious when recommending low carbohydrate diets, as they may increase the risk of type 2 diabetes, particularly in individuals with higher body weight.
GoodSupportsmedium confidence
Higher LCD score (p for trend = 0.001) was associated with increased risk of T2D. Quintile 5 (38 % energy from carbohydrates) versus quintile 1 (55 % energy from carbohydrates) showed a 20 % increased diabetes risk (incidence risk ratio (IRR) = 1.20 (95 % CI: 1.05-1.37)).
Why this rating
The study is a prospective cohort analysis.
Source
Association of low carbohydrate diet score with the risk of type 2 diabetes in an Australian population: A longitudinal study
Robel Hussen Kabthymer et al. · Diabetes & Metabolic Syndrome Clinical Research & Reviews · 2024
cohort · n=39185Cited 9×
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