Research
Hormonal
Real-world data suggest semaglutide use associates with reduced suicidal ideation and depression.
Semaglutide may have a beneficial effect on mental health, potentially reducing suicidal thoughts.
ModerateSupportsmedium confidence
Real-world data suggest semaglutide use associates with reduced suicidal ideation and depression.
Why this rating
Based on observational data, which is less robust than RCTs.
Source
Glucagon‐like‐peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association
Anthony Nguyen et al. · Clinical Obesity · 2024
DOI 10.1111/cob.12676
otherCited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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