Research
Molecular
Mendelian randomisation did not find evidence that genetically proxied GLP-1RA increased suicide attempts in a general population cohort.
There is no genetic evidence to support an association between GLP-1RA and increased suicide attempts, suggesting safety in this regard.
StrongRefutesmedium confidence
MR did not find evidence genetically proxied GLP1RA increased SA in a general population cohort.
Why this rating
Based on the use of Mendelian randomisation, which is a robust study design.
Source
Glucagon‐like‐peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association
Anthony Nguyen et al. · Clinical Obesity · 2024
otherCited 8×
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