Research
Metabolic adaptation
SGLT-2 inhibitors and GLP-1 receptor agonists (GLP-1RAs) lead to a decline in body weight ranging from 1.5 to 5 kg.
Practitioners can consider SGLT-2 inhibitors and GLP-1RAs as effective options for weight loss in patients.
StrongSupportsmedium confidence
All studies reported a decline in body weight following treatment with SGLT-2 inhibitors or GLP-1RAs, ranging from 1.5 to 5 kg.
Why this rating
Based on the systematic review of sixteen randomized controlled trials.
Source
The Emerging Role of Injectable Weight Loss Medications in Plastic Surgery: A Systematic Review
Sachin M. Shridharani et al. · Aesthetic Surgery Journal · 2023
DOI 10.1093/asj/sjad240
systematic_review · n=10492Cited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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