Research
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Obesity-targeted interventions are a novel treatment strategy for heart failure with preserved ejection fraction (HFpEF).
Healthcare providers should explore obesity-targeted interventions in managing HFpEF.
GoodSupportsmedium confidence
Consequently, obesity-targeted interventions have attracted attention as a novel treatment strategy for HFpEF.
Why this rating
Based on the review of literature and emerging strategies.
Source
Targeting obesity for therapeutic intervention in heart failure patients
Ryosuke Sato et al. · Expert Review of Cardiovascular Therapy · 2024
DOI 10.1080/14779072.2024.2363395
reviewCited 8×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- The STEP HFpEF and SELECT trials demonstrated that semaglutide improves clinical outcomes in obese HFpEF patients and reduces cardiovascular and heart failure events in non-diabetic obese patients.Strong
- Future clinical trials with other incretin mimetics may further emphasize the importance of an obesity phenotype-based approach in treating HFpEF.Limited
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