Research
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Finerenone has been associated with reduced cardiovascular mortality and total worsening HF events across all BMI levels, with greater benefits observed in patients with higher BMIs.
Finerenone may be a beneficial treatment option for reducing cardiovascular risks in patients with varying BMI levels.
StrongSupportsmedium confidence
Exploratory analyses of the nonsteroidal mineralocorticoid receptor antagonist finerenone has been associated with reduced cardiovascular mortality and total worsening HF events across all body mass index (BMI) levels, with greater benefits observed in patients with higher BMIs.
Why this rating
Based on exploratory analyses from clinical trials.
Source
Advances in the management of obesity and heart failure: latest evidence from clinical trials
Thomaz Alexandre Costa et al. · Current Opinion in Cardiology · 2025
DOI 10.1097/hco.0000000000001214
reviewCited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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