Research
Metabolic adaptation
Modest weight loss of 2-3% of body weight is recommended to improve therapeutic durability and prevent beta-cell deterioration.
Encouraging patients to achieve modest weight loss can enhance their diabetes management.
StrongSupportsmedium confidence
Modest weight loss with a goal of 2-3% of body weight should be recommended to improve therapeutic durability and prevent beta-cell deterioration.
Why this rating
Based on a systematic review and meta-analysis.
Source
Durability of glycaemic control in type 2 diabetes: A systematic review and meta‐analysis for its association with body weight changes
Danpei Li et al. · Diabetes Obesity and Metabolism · 2020
DOI 10.1111/dom.14217
Meta-analysisCited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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