Research
Energy balance
Metabolic and bariatric surgeries are the most effective strategy for significant weight loss in people living with severe obesity.
This reinforces the importance of considering surgical options for significant weight loss in severely obese patients.
StrongSupportsmedium confidence
Metabolic and bariatric surgeries have been shown to be the most effective strategy to induce and maintain significant weight loss for people living with severe obesity.
Why this rating
Based on established findings in the field.
Source
A commentary review on endoscopic sleeve gastroplasty: Indications, outcomes and future implications
Mahmoud Abuawwad et al. · Diabetes Obesity and Metabolism · 2024
DOI 10.1111/dom.15613
reviewCited 6×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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