Research
Energy balance
There are key knowledge gaps regarding long-term complications, microvascular and macrovascular events, and mortality associated with RYGB.
Further research is needed to understand the long-term risks associated with RYGB.
StrongQualifiesmedium confidence
Key knowledge gaps, particularly on long-term complications, microvascular- and macrovascular events, and mortality should be addressed.
Why this rating
Based on high-level evidence from randomized clinical trials.
Source
Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes
Tummas Justinussen et al. · Expert Review of Endocrinology & Metabolism · 2019
DOI 10.1080/17446651.2019.1628639
reviewCited 6×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Roux en-Y gastric bypass (RYGB) surgery is more effective than medical therapy in ameliorating the clinical manifestations of type 2 diabetes (T2D).Strong
- The postoperative incidence of beneficial effects and complications from RYGB varies across patient subgroups with different preoperative characteristics.Strong
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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