Research
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Semaglutide treatment is associated with improvements in quality of life (DLQI) and depressive symptoms (BDI) after 6 months.
Improving psoriasis treatment may also enhance mental health and quality of life.
GoodSupportsmedium confidence
along with improvements in DLQI, BDI and metabolic markers.
Why this rating
The study is a prospective cohort study.
Source
Dermatological and metabolic benefits of semaglutide in psoriasis with obesity: a 6-month prospective cohort study
Joana Nicolau et al. · Clinical and Experimental Dermatology · 2025
DOI 10.1093/ced/llaf473
cohort · n=43Cited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- After 6 months of semaglutide treatment, participants showed significant reductions in Psoriasis Area and Severity Index (PASI) by 48%, body mass index (BMI), and preperitoneal and superficial fat.Good
- Baseline disease severity, depressive symptoms, insulin resistance, and preperitoneal fat were negatively associated with PASI improvement.Good
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