Research
Hormonal
HEC-C070, with moderate GCG agonism, significantly affects weight loss and liver function in obese mice.
HEC-C070 may be a viable option for addressing obesity and liver function issues.
StrongSupportsmedium confidence
The GLP-1R selectivity of HEC-C070 with moderate GCG agonism has a significant effect on weight loss and liver function in obese mice.
Why this rating
Based on the evaluation of the compound's effects in a controlled study.
Source
The effects of Fc fusion protein glucagon-like peptide-1 and glucagon dual receptor agonist with different receptor selectivity in vivo studies
Peng Jiang et al. · Biomedicine & Pharmacotherapy · 2024
DOI 10.1016/j.biopha.2024.116485
otherCited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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