Research
Energy balance
Semaglutide led to a mean relative weight loss of 13.3 ± 11.3% after 12 months in adults with type 1 diabetes.
Practitioners can consider semaglutide as an effective option for weight management in overweight/obese patients with type 1 diabetes.
StrongSupportsmedium confidence
Mean relative weight loss was 13.3 ± 11.3% ( P < 0.001), with 76.4% attaining ≥5% weight loss and 61.7% attaining ≥10%.
Why this rating
Based on the real-world study design with a significant sample size.
Source
Real-World Evidence of the Effect of Adjunctive Semaglutide on Weight Change, Glycemic Control, and Metabolic Dysfunction-Associated Steatotic Liver Disease in People with Type 1 Diabetes
Jonathan Mertens et al. · Diabetes Technology & Therapeutics · 2025
DOI 10.1177/15209156251362497
cohort · n=42Cited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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