Research

Metabolic adaptation

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) decreased from 82.6% to 30.4% after treatment with semaglutide.

Semaglutide may significantly improve liver health in patients with type 1 diabetes and MASLD.

StrongSupportsmedium confidence
MASLD prevalence reduced from 82.6% to 30.4% ( P < 0.001).
Jonathan Mertens et al. · Diabetes Technology & Therapeutics · 2025

Why this rating

Based on the real-world study design with a significant sample size.

Source

Real-World Evidence of the Effect of Adjunctive Semaglutide on Weight Change, Glycemic Control, and Metabolic Dysfunction-Associated Steatotic Liver Disease in People with Type 1 Diabetes

Jonathan Mertens et al. · Diabetes Technology & Therapeutics · 2025

cohort · n=42Cited 3×
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