Research
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Semaglutide would be cost-effective at a threshold of $120,000 per QALY gained if the annual cost were lowered by 18% to $7,055.
Reducing the cost of semaglutide could enhance its affordability and accessibility for patients.
StrongSupportsmedium confidence
Semaglutide would be cost-effective at a threshold of $120 000 per QALY gained if the annual cost were lowered an additional 18% to $7055.
Why this rating
Based on a population-based cohort simulation study design.
Source
Cost-Effectiveness of Semaglutide for Secondary Prevention of Cardiovascular Disease in US Adults
Susan Hennessy et al. · JAMA Cardiology · 2026
DOI 10.1001/jamacardio.2025.5243
cohort · n=4000000Cited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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