Research
Metabolic adaptation
Significant reductions in diastolic BP (-1.5 mm Hg) and systolic BP (-1.1 mm Hg) were observed.
Semaglutide may help lower blood pressure in adults.
StrongSupportsmedium confidence
Significant reductions in diastolic BP (-1.5 mm Hg; 95% CI, -1.7 to -1.4 mm Hg) and systolic BP (-1.1 mm Hg; 95% CI, -1.4 to -0.8 mm Hg) were also observed.
Why this rating
Based on a large retrospective cohort study.
Source
Changes in Cardiovascular Risk Factors and Health Care Expenditures Among Patients Prescribed Semaglutide
Yuan Lu et al. · JAMA Network Open · 2025
DOI 10.1001/jamanetworkopen.2025.26013
cohort · n=23522Cited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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