Research
Molecular
Mitochondrial uncoupling promotes energy dissipation and may serve as a strategy for obesity treatment.
Practitioners may consider mitochondrial uncoupling as a potential target for obesity interventions.
StrongSupportsmedium confidence
One promising approach involves mitochondrial uncoupling, where electron transport and oxygen consumption are disconnected from ATP synthesis, promoting energy dissipation.
Why this rating
The claim is supported by preclinical studies mentioned in the abstract.
Source
Obesity and mitochondrial uncoupling – an opportunity for the carbon monoxide-based pharmacology of metabolic diseases
Aleksandra Danielak et al. · Pharmacological Research · 2025
DOI 10.1016/j.phrs.2025.107741
reviewCited 3×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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