Research
Energy balance
Weight loss was consistently larger in the incretin intervention groups than in placebo or lifestyle intervention comparators.
Incretin therapies may be more effective for weight loss compared to lifestyle changes or placebo.
StrongSupportsmedium confidence
Weight loss was consistently larger in the incretin intervention groups than in placebo or lifestyle intervention comparators.
Why this rating
Based on the study design of randomized controlled trials.
Source
Effect of Incretin-Based and Nonpharmacologic Weight Loss on Body Composition
John A. Batsis et al. · Annals of Internal Medicine · 2026
DOI 10.7326/annals-25-00478
rctCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →