Research
Metabolic adaptation
Loss of muscle-related indices exceeded prespecified benchmarks in two thirds of incretin-based interventions.
Clinicians should monitor muscle mass when prescribing incretin therapies for weight loss.
StrongSupportsmedium confidence
Loss of muscle-related indices exceeded prespecified benchmarks in two thirds of incretin-based interventions.
Why this rating
Based on the study design of randomized controlled trials.
Source
Effect of Incretin-Based and Nonpharmacologic Weight Loss on Body Composition
John A. Batsis et al. · Annals of Internal Medicine · 2026
DOI 10.7326/annals-25-00478
rctCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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