Research
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No significant associations were found between GLP-1 receptor agonists or SGLT2 inhibitors and risk of sepsis, abscess, gangrene, or other infections.
Practitioners can be reassured about the lack of infection risk associated with these medications.
StrongRefutesmedium confidence
No significant associations were found between any other GLP-1 receptor agonist or SGLT2 inhibitor and risk of sepsis, abscess, gangrene, or other infections.
Why this rating
Based on the analysis of 105 randomized controlled trials.
Source
The effect of GLP-1 receptor agonist and SGLT2 inhibitor on infection risk: network meta-analysis
Bing-Syuan Zeng et al. · Clinical Microbiology and Infection · 2026
DOI 10.1016/j.cmi.2026.01.014
Meta-analysisCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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