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Weight loss significantly explained heterogeneity in treatment effects on fibrosis improvement and MASH resolution.

Weight management should be emphasized in treatment plans for MASH to enhance treatment efficacy.

StrongSupportsmedium confidence
Meta‐regression using data from 16 interventions... showed that weight loss significantly explained heterogeneity in treatment effects on fibrosis improvement (R2 = 54.26%) and MASH resolution (R2 = 78.16%).
Mainak Banerjee et al. · Diabetes Obesity and Metabolism · 2025

Why this rating

Based on a meta-analysis of multiple interventions.

Source

Histological efficacy of anti‐diabetic agents in <scp>MASH</scp> and the mediating role of weight loss: A network meta‐analysis

Mainak Banerjee et al. · Diabetes Obesity and Metabolism · 2025

Meta-analysisCited 2×
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