Research
Energy balance
Both bariatric surgery and GLP-1RA treatment improve the fat-free mass (FFM) to fat mass (FM) ratio.
Both interventions are effective in improving body composition ratios.
StrongSupportsmedium confidence
FFM to FM ratios increased significantly in both groups, with surgical patients maintaining a higher ratio throughout.
Why this rating
Based on a large cohort study design.
Source
Body Composition Changes After Bariatric Surgery or Treatment With GLP-1 Receptor Agonists
Zicheng Wang et al. · JAMA Network Open · 2026
DOI 10.1001/jamanetworkopen.2025.53323
cohort · n=3066Cited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →