Research
Metabolic adaptation
MRs significantly reduce glycated hemoglobin (HbA1c) levels by 0.24%.
Using meal replacements can lead to better long-term glucose management.
StrongSupportsmedium confidence
The findings from 52 studies indicated significant reductions in HbA1c (WMD: -0.24%; 95% CI: -0.35%, -0.13%; P < .001).
Why this rating
Based on a meta-analysis of 52 studies.
Source
Effect of Total and Partial Meal Replacements on Factors Related to Glucose Metabolism: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Niloofar Sadat Maddahi et al. · Nutrition Reviews · 2025
Meta-analysisCited 2×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →