Research
Molecular
High fat feeding increases mTORC 1/2 complex formation by approximately 70% for Raptor and 60% for Rictor.
High fat diets significantly alter mTOR complex formation, which may impact muscle growth and metabolism.
StrongSupportsmedium confidence
The association of mTOR and its binding partners Raptor (p=0.02) and Rictor (p=0.03) were increased in HF by ~70% and ~60%, respectively.
Why this rating
Based on the study design involving direct measurements of protein complexes.
Source
Regulation of mTORC 1/2 Formation in Response to a High- fat Diet and Exercise Training.
Donato A. Rivas et al. · Medicine & Science in Sports & Exercise · 2008
DOI 10.1249/01.mss.0000321459.29650.32
otherCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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