Research
Molecular
Insulin stimulated S473 phosphorylation of Akt1 was increased by approximately 25% in a high-fat diet.
High-fat diets can enhance insulin signaling through Akt1, which may have implications for metabolic health.
StrongSupportsmedium confidence
Insulin stimulated S473 phosphorylation of Akt1 was increased by ~25% in HF (P<0.001).
Why this rating
Based on the study design involving direct measurements of phosphorylation.
Source
Regulation of mTORC 1/2 Formation in Response to a High- fat Diet and Exercise Training.
Donato A. Rivas et al. · Medicine & Science in Sports & Exercise · 2008
DOI 10.1249/01.mss.0000321459.29650.32
otherCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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