Research
Neural
The findings suggest potential neurobehavioral benefits associated with incretin-based therapies (IBTs) in a high-risk population.
These findings may guide clinicians in selecting appropriate treatments for patients at risk of AUD post-surgery.
StrongSupportsmedium confidence
These findings suggest potential neurobehavioral benefits associated with IBTs that may inform AOM selection in this high-risk population.
Why this rating
Based on a large retrospective cohort study design.
Source
Incretin-Based Therapies and Post–Bariatric Surgery Alcohol Use Disorder
Butros Fakhoury et al. · JAMA Network Open · 2025
DOI 10.1001/jamanetworkopen.2025.49086
cohort · n=15382Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Use of incretin-based therapies (IBT) after bariatric surgery is associated with a 55% lower risk of new-onset alcohol use disorder (AUD) compared to non-IBT antiobesity medications (AOMs).Strong
- IBT is associated with a 41% lower risk of initiation of medications for alcohol use disorder (MAUDs) compared to non-IBT AOMs.Strong
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