Research
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Hepatotoxicity is not a widely recognized complication of tirzepatide.
Awareness of potential liver injury should be increased among healthcare providers prescribing tirzepatide.
StrongSupportsmedium confidence
Hepatotoxicity is not a widely recognized complication of tirzepatide, and reported cases of liver injury are exceedingly rare.
Why this rating
Based on the case report format which provides direct evidence.
Source
Acute liver injury associated with tirzepatide: An unexpected adverse event warranting clinical attention
Bayan Saeed AlQarni et al. · Annales d Endocrinologie · 2026
DOI 10.1016/j.ando.2026.102485
case_studyCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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