Research
Cellular
Tirzepatide can cause acute hepatocellular liver injury in patients.
Clinicians should monitor liver function in patients using tirzepatide.
StrongSupportsmedium confidence
We report a case of a young, previously healthy female who developed acute hepatocellular liver injury several months after initiating tirzepatide therapy for weight loss.
Why this rating
Based on the case report format which provides direct evidence.
Source
Acute liver injury associated with tirzepatide: An unexpected adverse event warranting clinical attention
Bayan Saeed AlQarni et al. · Annales d Endocrinologie · 2026
DOI 10.1016/j.ando.2026.102485
case_studyCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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