Research
Neural
A gradual decrease in total body fat and no decrease in appendicular lean mass (ALM) are significantly independently associated with higher cognitive scores compared with other trajectories.
Weight loss strategies should focus on reducing body fat while preserving lean mass to support cognitive health.
StrongSupportsmedium confidence
A gradual decrease in total body fat and no decrease in ALM were significantly independently associated with higher cognitive scores compared with other trajectories.
Why this rating
Based on the large sample size and longitudinal study design.
Source
Association of body composition trajectories with changes in cognitive performance in the Look <scp>AHEAD</scp> study
Morgana Mongraw‐Chaffin et al. · Obesity · 2025
cohort · n=972Cited 1×
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