Research
Molecular
At average weight loss, the effect of a higher PS amounted to a change of 0.20-0.28 cm per standard deviation in WCadjBMI.
The small effect size suggests that genetic factors may have limited practical implications for weight loss interventions.
StrongSupportsmedium confidence
At average weight loss, this amounted to 0.20-0.28 cm per standard deviation.
Why this rating
Based on the design of the lifestyle intervention trials mentioned.
Source
Genetic Predictors of Change in Waist Circumference and Waist-To-Hip Ratio with Lifestyle Intervention: the Trans-NIH consortium for Genetics of Weight Loss Response to Lifestyle Intervention
Jeanne M. McCaffery et al. · 2022
other
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