Research
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Up to half of patients discontinue obesity medications within 1 to 2 years due to various reasons.
Practitioners should be aware of high discontinuation rates and address barriers to adherence.
StrongSupportsmedium confidence
up to half of patients discontinue treatment within 1 to 2 years due to side effects, limited access, cost, or inadequate response.
Why this rating
The claim is based on observed patient behavior.
Source
Approach to the Patient: Clinical Outcomes and Interim Strategies Following Discontinuation of Incretin Agonists
Sarah R. Barenbaum et al. · The Journal of Clinical Endocrinology & Metabolism · 2025
DOI 10.1210/clinem/dgaf641
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Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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