Research
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Discontinuation of obesity medications often results in weight regain and reversal of health benefits.
Practitioners should monitor patients for weight regain after discontinuation and implement strategies to mitigate this.
StrongSupportsmedium confidence
Discontinuation of OMs, however, often results in weight regain and reversal of associated health benefits.
Why this rating
The claim is based on observed outcomes following treatment cessation.
Source
Approach to the Patient: Clinical Outcomes and Interim Strategies Following Discontinuation of Incretin Agonists
Sarah R. Barenbaum et al. · The Journal of Clinical Endocrinology & Metabolism · 2025
DOI 10.1210/clinem/dgaf641
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Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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