Research
Hormonal
Female sex independently predicted greater TBWL, while insulin use and higher T2D medication burden were associated with less TBWL.
Understanding these predictors can help tailor treatment strategies for weight loss.
StrongSupportsmedium confidence
Female sex independently predicted greater TBWL, whereas insulin use, higher T2D medication burden (particularly weight-promoting agents), and HbA1c > 7% were associated with less TBWL.
Why this rating
Based on a retrospective analysis of a large cohort (717 adults).
Source
Leveraging the Individualized Metabolic Surgery Score to Predict Weight Loss with Tirzepatide in Adults with Type 2 Diabetes and Obesity
Regina Castaneda et al. · Diabetology · 2026
cohort · n=717
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