Research
Hormonal
Adding testosterone undecanoate to tirzepatide in late responders resulted in significantly greater body weight and fat mass reduction compared to tirzepatide monotherapy (P<0.05).
Clinicians may consider adding testosterone therapy to enhance weight loss outcomes in specific patient populations.
StrongSupportsmedium confidence
At 6 months, group B demonstrated significantly greater body weight and fat mass reduction compared to group A (P<0.05).
Why this rating
The study design involves a controlled comparison between two treatment groups.
Source
Effects of testosterone undecanoate as add-on therapy in obese hypogonadal men that are late responders to tirzepatide: a pilot study
Giuseppe Seminara et al. · Minerva Endocrinology · 2026
other · n=10
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