Research
Molecular
GLP-1R agonists raise cAMP levels in cardiac cells.
Understanding the role of cAMP may help in developing therapies targeting cardiac function.
StrongSupportsmedium confidence
Stimulation of GLP-1R in cell cultures... raised the activity of adenylyl cyclase and thus augmented the 3',5'cyclic adenosine monophosphate (cAMP) levels.
Why this rating
The study discusses experimental data related to cAMP levels.
Source
Acute Contractile Effects of Glucagon-like-Peptide-1 Receptor Agonists in the Human Heart
Joachim Neumann et al. · Pharmaceutics · 2026
other
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