Research
Metabolic adaptation
At 2.5 years, White individuals experienced significantly greater body weight loss than Black individuals: −7.1% versus −4.9%.
Practitioners should be aware of racial differences in weight loss outcomes when prescribing GLP-1RA therapy.
StrongSupportsmedium confidence
At 2.5 years, White individuals experienced significantly greater body weight loss than Black individuals: −7.1% (95% CI −8.0%, −6.2%) versus −4.9% (95% CI −5.4%, −4.3%).
Why this rating
Based on the analysis of a large cohort from EHR data.
Source
Responses to <scp>GLP</scp> ‐ <scp>1RA</scp> in White and Black Adults With Obesity: Insights From Generalized Additive Mixed Models of <scp>EHR</scp> Data
Jordan H Mallette et al. · Obesity · 2026
cohort · n=7214
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →