Research
Metabolic adaptation
White individuals had significantly larger reductions in estimated glomerular filtration rate, systolic blood pressure, and HbA1c compared to Black individuals.
Healthcare providers should consider these differences in clinical outcomes when treating patients with GLP-1RA.
StrongSupportsmedium confidence
White individuals... experienced... significantly larger reductions in estimated glomerular filtration rate, systolic blood pressure, and HbA1c.
Why this rating
Based on the analysis of a large cohort from EHR data.
Source
Responses to <scp>GLP</scp> ‐ <scp>1RA</scp> in White and Black Adults With Obesity: Insights From Generalized Additive Mixed Models of <scp>EHR</scp> Data
Jordan H Mallette et al. · Obesity · 2026
cohort · n=7214
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