Research

Metabolic adaptation

Incretin-based therapies lead to reduced ectopic fat depositions in multiple organs and favourable cardiac remodelling.

Incretin-based therapies may be effective in reducing harmful fat deposits and improving heart structure in affected patients.

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Incretin-based therapies... also leading to reduced ectopic fat depositions in multiple organs and favourable cardiac remodelling.
Masliza Mahmod et al. · Heart Failure Reviews · 2026

Why this rating

Based on emerging data indicating significant physiological changes.

Source

Reframing obesity-related HFpEF as a multiorgan syndrome: incretin-based therapies and imaging endpoints

Masliza Mahmod et al. · Heart Failure Reviews · 2026

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