Research
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Future clinical trials are needed to clarify the mechanisms of benefit and define the role of weight-reduction therapies in obesity-related HFpEF.
Clinicians should be aware that ongoing research may further inform treatment strategies for obesity-related HFpEF.
StrongSupportsmedium confidence
Future clinical trials incorporating multiorgan imaging endpoints... are needed to clarify the mechanisms of benefit and to better define the role of weight-reduction therapies in obesity-related HFpEF.
Why this rating
The call for future trials is based on the current understanding of the condition and therapies.
Source
Reframing obesity-related HFpEF as a multiorgan syndrome: incretin-based therapies and imaging endpoints
Masliza Mahmod et al. · Heart Failure Reviews · 2026
DOI 10.1007/s10741-026-10629-z
other
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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