Research
Energy balance
Tirzepatide treatment preserved lean mass and muscle function after 4 months.
Tirzepatide may help maintain muscle mass and function during weight loss in obese patients.
StrongSupportsmedium confidence
Lean mass was preserved (42.8 ± 16.8 vs. 41.8 ± 15.8 kg; p = 0.052), as was muscle function (31.6 ± 11.9 vs. 31.4 ± 11.6 kg; p = 0.5) after 4 months of treatment.
Why this rating
Based on the analysis of real-world data from a defined patient group.
Source
Tirzepatide in real-world clinical practice: changes in body composition and muscle function in patients with obesity
Jorge Blanco Anesto et al. · Nutrición Hospitalaria · 2026
DOI 10.20960/nh.06592
cohort · n=52
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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