Research
Energy balance
Cardiometabolic improvements from weight loss appear independent of changes in body fat percentage or fat distribution.
Weight loss alone may not lead to improvements in cardiometabolic health if body fat percentage or distribution does not change.
StrongSupportsmedium confidence
No cardiometabolic changes were associated with weight loss-adjusted changes in body fat percentage or fat distribution.
Why this rating
Based on the analysis of data from two structured interventions.
Source
Cardiometabolic Gains Unrelated to Weight Loss–Adjusted Body Fat or Distribution Changes in Adults With and Without Diabetes
Jose E. Galgani et al. · Obesity · 2026
DOI 10.1002/oby.70123
cohort
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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