Research
Neural
rCBF decreases in the hypothalamus and thalamus were attenuated in obese men compared with lean men.
This finding suggests that interventions may need to address specific brain region responses in obesity.
StrongSupportsmedium confidence
rCBF decreases in the hypothalamus and thalamus were attenuated in obese men compared with lean men (P < 0.05).
Why this rating
The study uses a reliable imaging technique with a clear comparison group.
Source
Differential brain responses to satiation in obese and lean men.
Jean–François Gautier et al. · Diabetes · 2000
DOI 10.2337/diabetes.49.5.838
cross-sectional · n=22Cited 286×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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