Research
Molecular
Variation at the leptin receptor gene (LEPR) is associated with obesity in humans.
Practitioners should consider genetic factors related to the leptin receptor when addressing obesity.
StrongSupportsmedium confidence
This demonstrates an association between variation at the leptin receptor gene and obesity in humans.
Why this rating
The study involves sequencing and identifying polymorphisms in a specific population.
Source
Structure and Sequence Variation at the Human Leptin Receptor Gene in Lean and Obese Pima Indians
D B Thompson et al. · Human Molecular Genetics · 1997
DOI 10.1093/hmg/6.5.675
other · n=20Cited 145×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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