Research
Molecular
Ubiquitin-protein conjugates were elevated at 2 days of immobilization (12%, p < 0.05) but were not different from baseline at 14 days.
Early increases in protein ubiquitination may indicate initial muscle stress, but this does not persist.
StrongSupportsmedium confidence
Ubiquitin-protein conjugates were elevated at 2 days of immobilization (12%, p < 0.05) but were not different from baseline at 14 days.
Why this rating
The statistical significance supports the reliability of the findings.
Source
Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophy
Elisa I. Glover et al. · Applied Physiology Nutrition and Metabolism · 2010
cohort · n=21Cited 79×
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