Research
Hormonal
Testosterone treatment further shortens the QTc interval in males with Klinefelter syndrome.
Testosterone therapy in males with KS may require monitoring of cardiac function due to its effects on QTc interval.
StrongSupportsmedium confidence
QTc was shortest among testosterone (T)-treated males with KS.
Why this rating
Based on the case-control study design with matched participants.
Source
Short QTc Interval in Males with Klinefelter Syndrome—Influence of CAG Repeat Length, Body Composition, and Testosterone Replacement Therapy
INGER NORLYK JØRGENSEN et al. · Pacing and Clinical Electrophysiology · 2015
DOI 10.1111/pace.12580
case_control · n=124Cited 53×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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