Research
Molecular
Males with Klinefelter syndrome (KS) have a shorter QTc interval compared to healthy controls.
Clinicians should be aware that males with KS may have altered cardiac function as indicated by QTc interval measurements.
StrongSupportsmedium confidence
Compared to controls, the QTc-interval was shorter (P = 0.02-0.06) in males with KS depending on the applied correction method.
Why this rating
Based on the case-control study design with matched participants.
Source
Short QTc Interval in Males with Klinefelter Syndrome—Influence of CAG Repeat Length, Body Composition, and Testosterone Replacement Therapy
INGER NORLYK JØRGENSEN et al. · Pacing and Clinical Electrophysiology · 2015
case_control · n=124Cited 53×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →