Research
Molecular
Untreated males with Klinefelter syndrome have a QTc interval comparable to healthy controls.
Untreated males with KS may not exhibit significant cardiac abnormalities compared to healthy individuals.
StrongSupportsmedium confidence
Untreated and thus hypogonadal KS had QTc interval comparable to controls.
Why this rating
Based on the case-control study design with matched participants.
Source
Short QTc Interval in Males with Klinefelter Syndrome—Influence of CAG Repeat Length, Body Composition, and Testosterone Replacement Therapy
INGER NORLYK JØRGENSEN et al. · Pacing and Clinical Electrophysiology · 2015
case_control · n=124Cited 53×
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