Research
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The meta-analysis included 12 RCTs with a total of 19,176 patients.
The large sample size strengthens the reliability of the findings.
StrongSupportsmedium confidence
The meta‐analysis included 12 RCTs, 69% for weight loss and 29% for smoking cessation, with 19,176 patients.
Why this rating
Based on meta-analysis of 12 RCTs.
Source
Cardiovascular safety of naltrexone and bupropion therapy: Systematic review and meta‐analyses
Andrei C. Spósito et al. · Obesity Reviews · 2021
DOI 10.1111/obr.13224
Meta-analysisCited 32×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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