Research
Metabolic adaptation
Patients with incident heart failure had 5.6% higher serum branched-chain amino acids (BCAAs) than those without heart failure (median 639.3 vs 605.2 μmol/L; P = .01).
Higher levels of BCAAs may indicate an increased risk of heart failure in patients with type 2 diabetes.
StrongSupportsmedium confidence
Patients with incident HF had 5.6% higher serum BCAAs than those without HF (median 639.3 [561.3‐756.3] vs 605.2 [524.8‐708.7] μmol/L; P = .01).
Why this rating
Based on the prospective observational study design.
Source
Circulating branched‐chain amino acids and incident heart failure in type 2 diabetes: The Hong Kong Diabetes Register
Lee‐Ling Lim et al. · Diabetes/Metabolism Research and Reviews · 2020
cohort · n=2139Cited 30×
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