Research
Metabolic adaptation
Serum BCAAs had a positive linear association with incident heart failure (hazard ratio [HR] 1.22 per-SD increase).
Monitoring BCAA levels may help assess heart failure risk in type 2 diabetes patients.
StrongSupportsmedium confidence
Serum BCAAs had a positive linear association with incident HF (per‐SD increase in logarithmically transformed BCAAs: hazard ratio [HR] 1.22 [95% CI 1.07‐1.39]).
Why this rating
Based on the prospective observational study design.
Source
Circulating branched‐chain amino acids and incident heart failure in type 2 diabetes: The Hong Kong Diabetes Register
Lee‐Ling Lim et al. · Diabetes/Metabolism Research and Reviews · 2020
cohort · n=2139Cited 30×
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