Research
Molecular
Statin-induced suppression of prenyl intermediates in the cholesterol biosynthetic pathway has been linked to stimulated atherosclerosis and heart failure.
Practitioners should be cautious about the long-term cardiovascular effects of statin use.
StrongSupportsmedium confidence
Statin-induced suppression of prenyl intermediates in the cholesterol biosynthetic pathway has been linked to stimulated atherosclerosis and heart failure.
Why this rating
The claim is based on established biochemical mechanisms.
Source
Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes
Harumi Okuyama et al. · Pharmacology · 2016
otherCited 30×
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