Research
Molecular
Statin-induced suppression of prenyl intermediates in the cholesterol biosynthetic pathway has been linked to stimulated atherosclerosis and heart failure.
Practitioners should be cautious about the long-term cardiovascular effects of statin use.
StrongSupportsmedium confidence
Statin-induced suppression of prenyl intermediates in the cholesterol biosynthetic pathway has been linked to stimulated atherosclerosis and heart failure.
Why this rating
The claim is based on established biochemical mechanisms.
Source
Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes
Harumi Okuyama et al. · Pharmacology · 2016
DOI 10.1159/000446704
otherCited 30×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Impaired vitamin K2-dependent processes by some types of vegetable oils and medicines are proposed as a cause of cardiovascular disease, diabetes, and other lifestyle-related diseases.Limited
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